Adenosquamous carcinoma of the liver

A 67-year-old man presented with a one-month history of poor oral intake and abdominal discomfort. He had a surgical history of gastric antrectomy due to a duodenal ulcer. A physical examination revealed mild distension of the abdomen, but no palpable mass. The serum level of alkaline phosphatase was 260 IU/L (normal range, 40-120 IU/L) and CA19-9 was 994.9 U/mL (normal range, 0-35 U/mL); other liver function tests were within normal limits. Serological tests for hepatitis B and hepatitis C virus showed negative. Abdominal computed tomography (CT) showed multiple peripheral enhancing masses in the right lobe of the liver (Fig. 1A). No abnormalities were found on systemic examinations. The patient underwent trisegmentectomy with regional lymph node dissection.